TABLE OF CONTENTS

I. Historical Background and Development of Cardiopulmonary Bypass A Chronology of Medical/ Technological Advances Michael S. Vinas, MA, RRT, CCP PerfCor International - Perfusion Education Website Prelude to the Historical Development of Mechanical Extracorporeal Circulation. Michael S. Vinas Administrator of Cardiovascular Perfusion Technology Bellevue Hospital Center New York Health and Hospitals Corporation

SECTION 1. ANATOMY 1. Cardiac Anatomy

Introduction to Cardiac Anatomy PediHeart. Cardiac Anatomy John Doty & Jill Rhead Cardiothoracic Surgical Network (CTSNet). Introduction to Cardiothoracic Imaging C. Carl Jaffe & Patrick J. Lynch - Yale University.

SECTION II - PHYSIOLOGY 1. Cardiovascular Physiology Cardiac Output Ever wonder what those numbers really mean ? Cardiac Muscle and Smooth Muscle Dr. Mariano J. Rey Department of Physiology New York University Cardiac Cicle Dr. Mariano J. Rey Department of Physiology New York University The Electrocardiogram Dr. Mariano J. Rey Department of Physiology New York University Basic EKG Dysrhythmia Identification Andrea Diane Posey, RN, MSN 12-lead ECG Library Homepage Dean Jenkins & Stephen Gerred The Hemodinamics of the Peripheral Circulation Dr. Mariano J. Rey Department of Physiology New York University Special Circulations Dr. Mariano J. Rey Department of Physiology New York University Neurohumoral Regulation of the Cardiovascular System Dr. Mariano J. Rey Department of Physiology New York University The Gross Physiology of the Cardiovascular System Robert M. Anderson, MD, FACC, FACS.

2. Respiratory Physiology Respiratory Physiology The Virtual Anesthesia Textbook John Loadsman Respiratory Physiology Dr Fred Roberts

3. Renal Physiology Water, Electrolytes, Renal and Acid-Base Renal and Acid-Base Physiology Ken Pauker Renal Physiology Slide Show D. C. Mikulecky - Faculty Mentoring Program Virginia Commonwealth University Renal Physiology Tutorial Website Prof. Mario Barac-Nieto Renal Physiology Revision Pauline Freeman

4. Blood Physiology Blood Physiology - An Introduction. Blood Groups John W. Kimball - Kimball's Biology Page. Blood Groups, Blood Typing and Blood Transfusions Nobel E-Museum ABO Blood Group System Robert J. Huskey Blood Groups - Hystocompatibility Dr. Eldon Sutton Blood Coagulation General Review of Blood Coagulation Blood Coagulation Doug Tollefsen Lab. Fibrinolysis Viera Stvtinova, Jan Jakubovsky and Ivan Hulín Recent Insights into the Hemostatic Mechanism Overview of Blood Coagulation.

5. Acid-Base Physiology Acid-Base Physiology Kerry Brandis Acid Base Tutorial Alan W. Grogono

SECTION III - CARDIAC PATHOLOGY 1. Congenital Heart Diseases Congenital Heart Diseases - Their Study and Treatment Oliver W. Caminos, M.D. Congenital Heart Disease Mayo Clinic Images - Slide Show Congenital Heart Diseases Library of Heart Diagrams: Royal Children's Hospital Melbourne, Australia Cardiovascular Pathology Index WebPath - The Internet Pathology Laboratory University of Utah - Pathology Laboratories Patent Ductus Arteriosus Kurt Plifieger - E-Medicine Coarctation of the Aorta Cincinnati Children's Hospital Medical Center - The Heart Center Encyclopedia Congenital Aortic Stenosis Mayo Clinic Medical Services, Rochester, USA. Aortopulmonary Septal Defect - Aorto-pulmonary Window Barry A Love, MD Vascular Rings/Slings Stephen H. McKellar. Atrial Septal Defect Ira H. Gessner - E-Medicine Ventricular Septal Defect Vibhuti N. Singh & Rakesh K. Sharma - E-Medicine Atrioventricular Septal Defect - Partial and Intermediate Michael A. Portman - E-Medicine Atrioventricular Septal Defect - Complete Michael McConnel & John Scheitler - E-Medicine Tetralogy of Fallot Kurt Pflieger, MD, FAAP Tetralogy of Fallot and Pulmonary Atresia Aparna Kulkarni & Michael Pettersen - E-Medicine Pulmonic Valvular Stenosis Kurt Pflieger, MD, FAAP D - Transposition of the Great Arteries John Charpie & Kevin Maher - E-Medicine Double Outlet Right Ventricle Rod Tarrago & Steven Neish - E-Medicine Ebstein's Anomaly CTSNet Publication - John Doty Total Anomalous Pulmonary Venous Connection and Cor Triatriatum CTSNet Publication - John Doty Left Ventricular Outflow Obstruction CTSNet Publications Valvar Aortic Stenosis Paul Seib, MD Supravalvar Aortic Stenosis Gautam K Singh, MD Aortic Valvular Stenosis Oliver W. Caminos, M.D. Ebstein's Anomaly Raymond T. Fedderly - E-Medicine Hypoplastic Left Heart Syndrome Daniel R. Turner & Thomas J. Forbes

2. Acquired Heart Diseases Myocardial Infarction - A Tutorial University of Utah - Pathology Laboratories Myocardial Infarction Sarah Stahmer, MD, FACEP & Shanon Brown, MD First Degree Heart Block David F.M. Brown, MD Second Degree Heart Block David F.M. Brown, MD Third Degree Heart Block David F.M. Brown, MD Aortic Regurgitation Jerry Balentine, MD & Elizabeth Kassapidis, MD Aortic Stenosis Jerry Balentine, MD & Anita Eisenhart, MD Aortic Dissection John Wiesenfarth, MD, MS Mitral Regurgitation Daniel DiSandro, MD Mitral Stenosis David K. Swain, MD & R. Kent Sargent, MD, FACEP Mitral Valve Prolapse Michael C. Plewa, MD, FAAEM

SECTION IV - CLINICAL CARDIOPULMONARY BYPASS 1. Neonatal, Infant & Pediatric Cardiopulmonary Bypass Pediatric x Adult Cardiopulmonary Bypass - Basic Comparison Kelly Calvert, BSN, CCP West Virginia University Hospital Current Updates in Pediatric Perfusion Handout: 1999 Jorge Molina, PA-C, CCP Pediatric Cardiothoracic Surgery Associates Children's Medical Center of Dallas Texas, U.S.A. Hypothermia in the Neonate and Infant Kelly Calvert, BSN, CCP West Virginia University Hospital Neonatal Post Cardiotomy Cardiac Assistance Clarke Thuys BAppSc, GradDipAppSc, CCP (Aust) Victorian Paediatric Cardiac Surgical Unit Royal Children's Hospital Melbourne, Victoria Australia Ventricular assist devices in pediatrics Fuchs A, Netz H. Images in Paediatric Cardiology To Wash or Not To Wash: Controlling Sodium, Glucose and Osmolarity In A Pediatric Extracorporeal Circuit Blood Prime Gary Grist RN, CCP. Chief Perfusionist - The Children's Mercy Hospitals and Clinics Kansas City, Missouri, USA Warm Intermittent Blood Microplegia in Pediatric Heart Surgery. Yves Durandy, MD. Pediatric Cardiac Surgery - Institut Cardiologique Paris Paris, France.

2. Adult Cardiopulmonary Bypass Conduct of Cardiovascular Perfusion - An Overview Michael S. Vinas, MS, CCP Weaning from Cardiopulmonary Bypass Maria Helena L. Souza, CCP (BR) & Decio O. Elias, MD Recombinant Activated Factor VII in the Management of Severe Hemorrhage following Cardiopulmonary Bypass * pdf version* Maria Helena L. Souza, CCP (BR) & Decio O. Elias, MD Carbon Dioxide Flooding the Operative Field to Minimize or Prevent Air Embolism During Open Heart Operations Bennett A. Mitchell, CCP Department of Cardiovascular Surgery, Montefiore Medical Center Albert Einstein School of Perfusion Technology Bronx, New York, USA Methods and Techniques to Reduce the use of Blood Components - Aprotinin Andre Luiz Tyszka, MD Cardiac Surgeon Maringa - Brazil Cardiopulmonary Bypass in Pregnant Patients Maria Helena L. Souza & Decio O. Elias Rio de Janeiro - Brazil Thermal Management Control for Cardiac Surgery Patients Ronald D. Nichols, B.S., C.C.P. William S. Middleton Memorial Veterans Hospital Madison, WI, USA Retrograde Autologous Priming ot Cardiopulmonary Bypass Circuit. Maria Helena L. Souza, CCP(Br) & Decio O. Elias, MD. Rio de Janeiro - Brazil Ventricular Assist Devices William S. Pierce, MD Mechanical Heart Assist Devices Texas Heart Institute Medical Technology Assessment for Ventricular Assist Devices Frank Baumeister, Jr., MD, Diane Lovell, Steven DeLashmutt, MD, Elaine Dunda, John T. Hoggard, MD, Herb Matter, David Noall, MD, Joanna Zamora, RN, Dan Harris, PhD. Electrophysiological evaluation of phrenic nerve injury during cardiac surgery - a prospective, controlled, clinical study. Download the article in pdf format Suat Canbaz, Nilda Turgut, Umit Halici, Kemal Balci, Turan Ege and Enver Duran. Trakaya University, Medical Faculty, Edime, Turkey Intra-Aortic Balloon Counterpulsation Eduardo Benchimol Saad, MD Intra-Aortic Balloon Pump Education and Therapy CPR Works Intra Aortic Balloon Pump (IABP) Counterpulsation Robert J. Mathews Advances in Myocardial Protection Refeng Yao, M.D. and Jianxiong An, M.D.

3. COMPLEMENTARY TECHNIQUES Blood Management - A Primer for Clinicians. Bradley A. Boucher, Pharm.D., FCCP, FCCM; Timothy J. Hannon, M.D., M.B.A.